Computed Tomography Coronary Angiography for the Prevention of Myocardial Infarction (The SCOT-HEART 2 Trial)
It is hypothesised that, in individuals being considered for cardiovascular preventative therapy, computed tomography coronary angiography guided management will reduce the future risk of coronary heart disease death or non-fatal myocardial infarction compared to management guided by the current standard of care, a cardiovascular risk score.
• ≥40 and ≤70 years of age
• Resident in Scotland and have a Community Health Index (CHI) number
• One or more of the following risk factors:
‣ \>60 years of age
⁃ Current or recent (within 12 months) smoker
⁃ Clinical diagnosis of hypertension
⁃ Known hypercholesterolaemia or total cholesterol \>6.0 mmol/L or receiving statin therapy
⁃ Diabetes mellitus
⁃ Rheumatoid arthritis
⁃ Systemic lupus erythematosus (SLE)
⁃ Family history of premature cardiovascular disease (first degree relative with atherosclerotic cardiovascular disease below 60 years)
⁃ Chronic kidney disease stage 3 (estimate glomerular filtration rate 30-59 mL/min/1.73 m2).